TİLMOZİN

For oral administration in livestock

• Demonstrates high effectiveness during respiratory infections

• Is well absorbed and distributed in the body and tissues

• Possesses bacteriostatic effects against a broad spectrum of gram-positive and gram-negative bacteria, especially Mycoplasma spp.

• Does not form precipitates in water at any temperature

Composition (per 1 liter):

Tilmicosin (as tilmicosin phosphate) – 250 mg

Indications:

For pigs with respiratory diseases caused by Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Pasteurella multocida; for poultry with infections caused by Mycoplasma gallisepticum, Mycoplasma synoviae, Ornithobacterium rhinotracheale, Pasteurella multocida; for cattle with respiratory infections caused by Pasteurella multocida, Mannheimia haemolytica, Arcanobacterium pyogenes, Mycoplasma bovis, Mycoplasma dyspar, as well as mixed infections, secondary bacterial infections during viral diseases, and other diseases sensitive to tilmicosin.

Dosage:

• Poultry: In group treatment, the daily dose of tilmicosin is 300 ml of Tilmozin added to 1000 liters of drinking water (equivalent to 75 mg of tilmicosin per 1 liter of water) for 3-5 days.

• Pigs: In group treatment, the daily dose of tilmicosin is 800 ml of Tilmozin added to 1000 liters of drinking water (equivalent to 200 mg of tilmicosin per 1 liter of water) for 5 days.

• Cattle: Individually, tilmicosin can be added to drinking water or milk replacer at a rate of 0.5 ml per 10 kg of body weight (equivalent to 12.5 mg of tilmicosin per 1 kg of body weight) for 5-7 days.

Withdrawal Period:

• Poultry: 16 days

• Pigs: 16 days

• Cattle: 35 days

Tilmicosin - Effective treatment for respiratory diseases

Tilmicosin is a semi-synthetic antibiotic from the macrolide group, derived from tylosin. It has a broad spectrum of activity against gram-positive and gram-negative bacteria, including Pasteurella spp., Haemophilus spp., Actinomyces spp., Corynebacterium spp., as well as against mycoplasmas (Mycoplasma gallisepticum, M. synoviae, M. Iovae).

The bacteriostatic effect of tilmicosin is based on blocking ribosomal synthesis at the cellular level, disrupting protein production. When administered orally, tilmicosin sulfate is well absorbed from the digestive tract and is rapidly distributed throughout the body and tissues, reaching maximal blood levels within 1.5 - 3 hours. The therapeutic concentration remains in the body for 18 - 24 hours. Tilmicosin is primarily excreted unchanged, with a portion being eliminated in urine and partially in feces.